Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk

Abstract In mice, periodic cycles of a fasting mimicking diet (FMD) protect normal cells while killing damaged cells including cancer Guarana and autoimmune cells, reduce inflammation, promote multi-system regeneration, and extend longevity.Here, we performed secondary and exploratory analysis of blood samples from a randomized clinical trial (NCT0

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Ultrasound-Guided Partial Release of Transverse Carpal Ligament in Severe Carpal Tunnel Syndrome Using a Curved Needle

Ultrasound (US) is an excellent Ball - Bag - Personal tool for diagnosis and management of carpal tunnel syndrome (CTS).Severe, recalcitrant CTS is an indication for complete release of the transverse carpal ligament (TCL).However, complete TCL release may be associated with postprocedural pillar pain.US-guided partial division of the TCL using a S

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N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages.

N6-methyladenosine (m6A) is a prevalent RNA modification that plays a key role in regulating eukaryotic cellular mRNA functions.RNA m6A modification is regulated by two groups of cellular proteins, writers and erasers that add or remove m6A, respectively.HIV-1 RNA contains m6A modifications that modulate viral infection and gene expression in CD4+

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Population attributable fraction in textbooks: Time to revise

Introduction: The population attributable fraction is an important measure for assessing the impact of intervention on the disease risk in populations, but it is frequently misused in the research literature.Methods: Accessories In this study, we review the definition, calculation, interpretation and assumptions of PAF in 43 textbooks and highlight

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